S25L (p.Ser25Leu) variant of WDR19 (WD repeat-containing protein 19)
S25L (p.Ser25Leu) in WDR19 (WD repeat-containing protein 19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
S25L (p.Ser25Leu) variant details
- p.Ser25Leu
- gnomAD 4-39185793-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.11
- ESM-1b 0.84
- AlphaMissense 0.06
- MetaLR 0.01
- MetaSVM -0.88
- CADD 22.40
- Population evidence available
- Structural context available
- Literature evidence available