S25A (p.Ser25Ala) variant of WDR19 (WD repeat-containing protein 19)
S25A (p.Ser25Ala) in WDR19 (WD repeat-containing protein 19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
S25A (p.Ser25Ala) variant details
- p.Ser25Ala
- gnomAD 4-39185792-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.231
- REVEL 0.10
- ESM-1b 0.15
- AlphaMissense 0.06
- MetaLR 0.01
- MetaSVM -0.94
- CADD 20.60
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available