D35H (p.Asp35His) variant of WDR19 (WD repeat-containing protein 19)
D35H (p.Asp35His) in WDR19 (WD repeat-containing protein 19) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
D35H (p.Asp35His) variant details
- p.Asp35His
- TOPMed rs1725576053
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.27
- ESM-1b 1.00
- AlphaMissense 0.45
- MetaLR 0.05
- MetaSVM -1.14
- CADD 24.90
- Most common in the HGDP:BANTUSOUTHAFRICA population (allele frequency 0.062)
- Structural context available