Y87S (p.Tyr87Ser) variant of VWF (von Willebrand factor)
Y87S (p.Tyr87Ser) in VWF (von Willebrand factor) is a missense change. The available record places it in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
Y87S (p.Tyr87Ser) variant details
- p.Tyr87Ser
- rs62643621
- ClinGen CA228355
- ClinVar RCV000086622
- TOPMed rs62643621
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.38
- MetaLR 0.28
- MetaSVM -0.58
- CADD 24.50
- PolyPhen-2 1.00
- SIFT 0.00
- ClinVar: not provided (not provided)
- UniProt: Not provided
- Most common in the REMAINING population (allele frequency 5e-05)
- Structural context available