R153S (p.Arg153Ser) variant of VWF (von Willebrand factor)
R153S (p.Arg153Ser) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
R153S (p.Arg153Ser) variant details
- p.Arg153Ser
- gnomAD rs1945295126
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.24
- MetaLR 0.21
- MetaSVM -0.64
- CADD 24.00
- PolyPhen-2 0.99
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available