P3S (p.Pro3Ser) variant of VWF (von Willebrand factor)
P3S (p.Pro3Ser) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
P3S (p.Pro3Ser) variant details
- p.Pro3Ser
- TOPMed rs1314021275
- gnomAD rs1314021275
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.07
- MetaLR 0.16
- MetaSVM -0.99
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available