M111T (p.Met111Thr) variant of VWF (von Willebrand factor)
M111T (p.Met111Thr) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
M111T (p.Met111Thr) variant details
- p.Met111Thr
- gnomAD rs1349554783
- Missense
- Variant Prioritization Score for Impact Estimate 0.29
- REVEL 0.20
- MetaLR 0.11
- MetaSVM -1.02
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available