M111L (p.Met111Leu) variant of VWF (von Willebrand factor)
M111L (p.Met111Leu) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
M111L (p.Met111Leu) variant details
- p.Met111Leu
- TOPMed rs1262180179
- gnomAD rs1262180179
- Missense
- Variant Prioritization Score for Impact Estimate 0.108
- REVEL 0.05
- MetaLR 0.04
- MetaSVM -1.01
- CADD 6.02
- PolyPhen-2 0.02
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available