M111K (p.Met111Lys) variant of VWF (von Willebrand factor)
M111K (p.Met111Lys) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M111K (p.Met111Lys) variant details
- p.Met111Lys
- gnomAD rs1349554783
- Missense
- Variant Prioritization Score for Impact Estimate 0.401
- REVEL 0.40
- MetaLR 0.22
- MetaSVM -0.70
- CADD 23.70
- PolyPhen-2 0.13
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available