M111I (p.Met111Ile) variant of VWF (von Willebrand factor)
M111I (p.Met111Ile) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
M111I (p.Met111Ile) variant details
- p.Met111Ile
- Ensembl rs1945297597
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.08
- MetaLR 0.06
- MetaSVM -1.07
- CADD 19.00
- PolyPhen-2 0.04
- SIFT 0.95
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available