G25R (p.Gly25Arg) variant of VWF (von Willebrand factor)
G25R (p.Gly25Arg) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
G25R (p.Gly25Arg) variant details
- p.Gly25Arg
- ExAC rs768896863
- gnomAD rs768896863
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.02
- MetaLR 0.08
- MetaSVM -1.00
- CADD 8.31
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available