F91I (p.Phe91Ile) variant of VWF (von Willebrand factor)
F91I (p.Phe91Ile) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
F91I (p.Phe91Ile) variant details
- p.Phe91Ile
- ExAC rs760170954
- TOPMed rs760170954
- gnomAD rs760170954
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- REVEL 0.23
- MetaLR 0.28
- MetaSVM -0.58
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.04
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available