F6L (p.Phe6Leu) variant of VWF (von Willebrand factor)
F6L (p.Phe6Leu) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
F6L (p.Phe6Leu) variant details
- p.Phe6Leu
- TOPMed rs1374009057
- gnomAD rs1374009057
- Missense
- Variant Prioritization Score for Impact Estimate 0.0672
- REVEL 0.01
- MetaLR 0.02
- MetaSVM -1.01
- CADD 1.05
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available