D106N (p.Asp106Asn) variant of VWF (von Willebrand factor)
D106N (p.Asp106Asn) in VWF (von Willebrand factor) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
D106N (p.Asp106Asn) variant details
- p.Asp106Asn
- TOPMed rs1945300348
- Missense
- Variant Prioritization Score for Impact Estimate 0.169
- REVEL 0.06
- MetaLR 0.14
- MetaSVM -1.02
- CADD 17.20
- PolyPhen-2 0.50
- SIFT 0.12
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available