Y67H (p.Tyr67His) variant of VPS35 (Q96QK1)
Y67H (p.Tyr67His) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data and structural context.
Y67H (p.Tyr67His) variant details
- p.Tyr67His
- gnomAD rs1211485116
- Missense
- Variant Prioritization Score for Impact Estimate 0.741
- REVEL 0.80
- CADD 28.40
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available