V23G (p.Val23Gly) variant of VPS35 (Q96QK1)
V23G (p.Val23Gly) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data and structural context.
V23G (p.Val23Gly) variant details
- p.Val23Gly
- Ensembl rs996986541
- Missense
- Variant Prioritization Score for Impact Estimate 0.769
- REVEL 0.84
- CADD 29.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available