T222P (p.Thr222Pro) variant of VPS35 (Q96QK1)
T222P (p.Thr222Pro) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
T222P (p.Thr222Pro) variant details
- p.Thr222Pro
- Ensembl rs1966192831
- Missense
- Variant Prioritization Score for Impact Estimate 0.603
- REVEL 0.56
- CADD 27.70
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the 1KG:BEB population (allele frequency 0.0053)
- Structural context available