S177N (p.Ser177Asn) variant of VPS35 (Q96QK1)
S177N (p.Ser177Asn) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S177N (p.Ser177Asn) variant details
- p.Ser177Asn
- gnomAD rs1186313084
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.15
- CADD 16.80
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available