R211G (p.Arg211Gly) variant of VPS35 (Q96QK1)
R211G (p.Arg211Gly) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
R211G (p.Arg211Gly) variant details
- p.Arg211Gly
- gnomAD rs1472271060
- Missense
- Variant Prioritization Score for Impact Estimate 0.297
- REVEL 0.19
- CADD 23.80
- PolyPhen-2 0.51
- SIFT 0.02
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available