Q277R (p.Gln277Arg) variant of VPS35 (Q96QK1)
Q277R (p.Gln277Arg) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
Q277R (p.Gln277Arg) variant details
- p.Gln277Arg
- ExAC rs760891909
- gnomAD rs760891909
- Missense
- Variant Prioritization Score for Impact Estimate 0.43
- REVEL 0.33
- CADD 22.30
- PolyPhen-2 0.01
- SIFT 0.40
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available