P162T (p.Pro162Thr) variant of VPS35 (Q96QK1)
P162T (p.Pro162Thr) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
P162T (p.Pro162Thr) variant details
- p.Pro162Thr
- ExAC rs777932822
- gnomAD rs777932822
- Missense
- Variant Prioritization Score for Impact Estimate 0.8
- REVEL 0.89
- CADD 26.00
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available