E170G (p.Glu170Gly) variant of VPS35 (Q96QK1)
E170G (p.Glu170Gly) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
E170G (p.Glu170Gly) variant details
- p.Glu170Gly
- TOPMed rs1966194476
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.20
- CADD 23.30
- PolyPhen-2 0.00
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available