A22G (p.Ala22Gly) variant of VPS35 (Q96QK1)
A22G (p.Ala22Gly) in VPS35 (Q96QK1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
A22G (p.Ala22Gly) variant details
- p.Ala22Gly
- gnomAD rs1254449170
- Missense
- Variant Prioritization Score for Impact Estimate 0.415
- REVEL 0.17
- CADD 25.10
- PolyPhen-2 0.19
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available