W5L (p.Trp5Leu) variant of VKORC1 (Q9BQB6)
W5L (p.Trp5Leu) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
W5L (p.Trp5Leu) variant details
- p.Trp5Leu
- ExAC rs752892359
- TOPMed rs752892359
- gnomAD rs752892359
- Missense
- Variant Prioritization Score for Impact Estimate 0.625
- REVEL 0.59
- CADD 24.30
- PolyPhen-2 0.87
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available