W5C (p.Trp5Cys) variant of VKORC1 (Q9BQB6)
W5C (p.Trp5Cys) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
W5C (p.Trp5Cys) variant details
- p.Trp5Cys
- TOPMed rs1008191003
- gnomAD rs1008191003
- Missense
- Variant Prioritization Score for Impact Estimate 0.608
- REVEL 0.57
- CADD 24.00
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available