W10S (p.Trp10Ser) variant of VKORC1 (Q9BQB6)
W10S (p.Trp10Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
W10S (p.Trp10Ser) variant details
- p.Trp10Ser
- ExAC rs766721996
- gnomAD rs766721996
- Missense
- Variant Prioritization Score for Impact Estimate 0.51
- REVEL 0.61
- CADD 22.80
- PolyPhen-2 0.12
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available