W10* (p.Trp10Ter) variant of VKORC1 (Q9BQB6)
W10* (p.Trp10Ter) in VKORC1 (Q9BQB6) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
W10* (p.Trp10Ter) variant details
- p.Trp10Ter
- ExAC rs763425395
- TOPMed rs763425395
- gnomAD rs763425395
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.496
- CADD 34.00
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available