V21L (p.Val21Leu) variant of VKORC1 (Q9BQB6)
V21L (p.Val21Leu) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
V21L (p.Val21Leu) variant details
- p.Val21Leu
- Ensembl rs2057316166
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.23
- CADD 12.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 3.4e-06)
- Structural context available