V11L (p.Val11Leu) variant of VKORC1 (Q9BQB6)
V11L (p.Val11Leu) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
V11L (p.Val11Leu) variant details
- p.Val11Leu
- 1000Genomes rs547713296
- TOPMed rs547713296
- gnomAD rs547713296
- Missense
- Variant Prioritization Score for Impact Estimate 0.313
- REVEL 0.35
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available