T4S (p.Thr4Ser) variant of VKORC1 (Q9BQB6)
T4S (p.Thr4Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
T4S (p.Thr4Ser) variant details
- p.Thr4Ser
- ExAC rs756150795
- gnomAD rs756150795
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- REVEL 0.24
- CADD 16.40
- PolyPhen-2 0.00
- SIFT 0.35
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available