T4N (p.Thr4Asn) variant of VKORC1 (Q9BQB6)
T4N (p.Thr4Asn) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T4N (p.Thr4Asn) variant details
- p.Thr4Asn
- ExAC rs756150795
- gnomAD rs756150795
- Missense
- Variant Prioritization Score for Impact Estimate 0.335
- REVEL 0.32
- CADD 17.70
- PolyPhen-2 0.04
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 5e-05)
- Structural context available