T4A (p.Thr4Ala) variant of VKORC1 (Q9BQB6)
T4A (p.Thr4Ala) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
T4A (p.Thr4Ala) variant details
- p.Thr4Ala
- ExAC rs749237507
- TOPMed rs749237507
- gnomAD rs749237507
- Missense
- Variant Prioritization Score for Impact Estimate 0.352
- REVEL 0.28
- CADD 16.30
- PolyPhen-2 0.01
- SIFT 0.31
- Most common in the Non-Finnish European population (allele frequency 4.5e-06)
- Structural context available