T18M (p.Thr18Met) variant of VKORC1 (Q9BQB6)
T18M (p.Thr18Met) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
T18M (p.Thr18Met) variant details
- p.Thr18Met
- gnomAD rs1458185698
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.32
- CADD 14.80
- PolyPhen-2 0.10
- SIFT 0.14
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available