S81T (p.Ser81Thr) variant of VKORC1 (Q9BQB6)
S81T (p.Ser81Thr) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
S81T (p.Ser81Thr) variant details
- p.Ser81Thr
- gnomAD 16-31093353-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.738
- REVEL 0.70
- CADD 26.70
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available