S7N (p.Ser7Asn) variant of VKORC1 (Q9BQB6)
S7N (p.Ser7Asn) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
S7N (p.Ser7Asn) variant details
- p.Ser7Asn
- ExAC rs755166588
- TOPMed rs755166588
- gnomAD rs755166588
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.25
- CADD 7.74
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 5.8e-05)
- Structural context available