S23W (p.Ser23Trp) variant of VKORC1 (Q9BQB6)
S23W (p.Ser23Trp) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
S23W (p.Ser23Trp) variant details
- p.Ser23Trp
- TOPMed rs1414049720
- gnomAD rs1414049720
- Missense
- Variant Prioritization Score for Impact Estimate 0.813
- REVEL 0.83
- CADD 27.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the HGDP:BIAKA population (allele frequency 0.93)
- Structural context available