R35W (p.Arg35Trp) variant of VKORC1 (Q9BQB6)
R35W (p.Arg35Trp) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
R35W (p.Arg35Trp) variant details
- p.Arg35Trp
- ExAC rs762195886
- TOPMed rs762195886
- gnomAD rs762195886
- Missense
- Variant Prioritization Score for Impact Estimate 0.818
- REVEL 0.81
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available