R35Q (p.Arg35Gln) variant of VKORC1 (Q9BQB6)
R35Q (p.Arg35Gln) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data and structural context.
R35Q (p.Arg35Gln) variant details
- p.Arg35Gln
- TOPMed rs1024627160
- gnomAD rs1024627160
- Missense
- Variant Prioritization Score for Impact Estimate 0.609
- REVEL 0.64
- CADD 26.00
- PolyPhen-2 1.00
- SIFT 0.09
- Most common in the HGDP:MBUTI population (allele frequency 0.083)
- Structural context available