R35G (p.Arg35Gly) variant of VKORC1 (Q9BQB6)
R35G (p.Arg35Gly) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
R35G (p.Arg35Gly) variant details
- p.Arg35Gly
- ExAC rs762195886
- TOPMed rs762195886
- gnomAD rs762195886
- Missense
- Variant Prioritization Score for Impact Estimate 0.805
- REVEL 0.83
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 2.3e-05)
- Structural context available