R33H (p.Arg33His) variant of VKORC1 (Q9BQB6)
R33H (p.Arg33His) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
R33H (p.Arg33His) variant details
- p.Arg33His
- gnomAD rs1391461576
- Missense
- Variant Prioritization Score for Impact Estimate 0.4
- REVEL 0.42
- CADD 21.70
- PolyPhen-2 0.01
- SIFT 0.17
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available