R12W (p.Arg12Trp) variant of VKORC1 (Q9BQB6)
R12W (p.Arg12Trp) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.71 / 1. The record also includes population frequency data and structural context.
R12W (p.Arg12Trp) variant details
- p.Arg12Trp
- TOPMed rs1238672542
- Missense
- Variant Prioritization Score for Impact Estimate 0.712
- REVEL 0.91
- CADD 27.30
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available