N77H (p.Asn77His) variant of VKORC1 (Q9BQB6)
N77H (p.Asn77His) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.74 / 1. The record also includes population frequency data, published literature, and structural context.
N77H (p.Asn77His) variant details
- p.Asn77His
- gnomAD 16-31093366-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.742
- REVEL 0.81
- CADD 27.70
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0011)
- Structural context available
- Literature evidence available