L76P (p.Leu76Pro) variant of VKORC1 (Q9BQB6)
L76P (p.Leu76Pro) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
L76P (p.Leu76Pro) variant details
- p.Leu76Pro
- gnomAD 16-31093368-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.88
- CADD 31.00
- PolyPhen-2 0.92
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available