L76F (p.Leu76Phe) variant of VKORC1 (Q9BQB6)
L76F (p.Leu76Phe) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
L76F (p.Leu76Phe) variant details
- p.Leu76Phe
- gnomAD 16-31093369-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.422
- REVEL 0.46
- CADD 21.40
- PolyPhen-2 0.02
- SIFT 0.21
- Population evidence available
- Structural context available
- Literature evidence available