L65F (p.Leu65Phe) variant of VKORC1 (Q9BQB6)
L65F (p.Leu65Phe) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data, published literature, and structural context.
L65F (p.Leu65Phe) variant details
- p.Leu65Phe
- gnomAD 16-31093464-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.477
- CADD 9.33
- Most common in the Ashkenazi Jewish population (allele frequency 5.1e-05)
- Structural context available
- Literature evidence available