I82V (p.Ile82Val) variant of VKORC1 (Q9BQB6)
I82V (p.Ile82Val) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
I82V (p.Ile82Val) variant details
- p.Ile82Val
- ExAC rs781032482
- TOPMed rs781032482
- gnomAD rs781032482
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.28
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available