I82T (p.Ile82Thr) variant of VKORC1 (Q9BQB6)
I82T (p.Ile82Thr) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
I82T (p.Ile82Thr) variant details
- p.Ile82Thr
- gnomAD rs1454769993
- Missense
- Variant Prioritization Score for Impact Estimate 0.673
- REVEL 0.72
- CADD 24.80
- PolyPhen-2 0.42
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available