G84S (p.Gly84Ser) variant of VKORC1 (Q9BQB6)
G84S (p.Gly84Ser) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data and structural context.
G84S (p.Gly84Ser) variant details
- p.Gly84Ser
- ExAC rs751483513
- TOPMed rs751483513
- gnomAD rs751483513
- Missense
- Variant Prioritization Score for Impact Estimate 0.812
- REVEL 0.82
- CADD 28.00
- PolyPhen-2 0.84
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 7.7e-05)
- Structural context available