G84R (p.Gly84Arg) variant of VKORC1 (Q9BQB6)
G84R (p.Gly84Arg) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.79 / 1. The record also includes population frequency data, published literature, and structural context.
G84R (p.Gly84Arg) variant details
- p.Gly84Arg
- gnomAD 16-31093345-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.792
- REVEL 0.82
- CADD 24.40
- PolyPhen-2 0.33
- SIFT 0.00
- Most common in the East Asian population (allele frequency 2.8e-05)
- Structural context available
- Literature evidence available