G6R (p.Gly6Arg) variant of VKORC1 (Q9BQB6)
G6R (p.Gly6Arg) in VKORC1 (Q9BQB6) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
G6R (p.Gly6Arg) variant details
- p.Gly6Arg
- gnomAD rs2057317246
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.22
- CADD 7.36
- PolyPhen-2 0.00
- SIFT 0.92
- Most common in the Non-Finnish European population (allele frequency 9.9e-07)
- Structural context available